About Parabilis Medicines At Parabilis Medicines, we are redefining what's possible in drug discovery. We are a clinical-stage biopharmaceutical company dedicated to creating unique and extraordinary medicines for patients with serious diseases by unlocking biologically important targets long considered beyond the reach of conventional medicines. Our intent is to create an important long-lived company, partnering with the right investors at different points of our growth. Our proprietary Helicon™ platform has pioneered a new class of stabilized alpha-helical peptides capable of modulating intracellular proteins that have historically been considered "undruggable." Our lead investigational medicine, zolucatetide, is the first and only direct inhibitor of the β-catenin interaction that has demonstrated compelling early clinical activity across a range of Wnt/β-catenindriven diseases, including desmoid tumors, familial adenomatous polyposis (FAP), adamantinomatous craniopharyngioma (ACP), hepatocellular carcinoma (HCC) and other solid tumor indications. We are also advancing a growing pipeline of additional medicines including franchiseextended beta catenin degraders, and Helicon peptides targeting prostate cancer and a range of other cancers. Our platform is advanced and continues to evolve in its reach of the most important protein causal drivers of diseases. Our mission is clear: transform the lives of more patients, and their families and communities. As a member of the Parabilis team, you'll work alongside scientists, clinicians, and innovators who are driven by curiosity, collaboration, and a shared commitment to tackling some of the most difficult challenges in medicine. Together, we're building the next generation of therapies for patients who need them most. For more information, visit www.parabilismed.com or follow us on LinkedIn. What’s the opportunity? The Head of Investor Relations is responsible for developing and implementing the IR strategy and and operations for Parabilis Medicines. The role will be responsible for sophisticated development and maintenance of the investor community and serve as Parabilis’ company contact. Our current and potential investors will have varying understanding of the details of our value proposition, and the IR head is expected to understand and propose measures to fill gaps and course correct as appropriate. Our investors will evolve over time, and it is expected that the head of IR will anticipate these changes and continuously plan ahead. Reporting to the CFO and partnering closely with the CEO, the CBSO, Corporate Communications and the broader Senior Management Team, this person will drive and execute on our strategic objectives with the investor community and be responsible for relationship management with current and prospective shareholders and financial analysts. Responsibilities: - Partner with the CEO and CFO to enhance and drive forward a strategic IR plan and strategy to effectively convey Parabilis’ story and value proposition to both the sell-side and buy-side with a goal of expanding the investor base. - Work closely with the CBSO and Corporate Communications to adapt the broader corporate narrative and messaging to current and potential investors. - Create a strategy and tactical plan to continuously deepen interest from our most important current and target investors, and a multi-year plan to evolve this investor base alongside our own evolution. - Working closely with the CEO and CFO to lead and manage Parabilis’ participation on quarterly earnings calls, investment conference calls and in-house meetings, road shows, analyst days, and one-on-one meetings. - Develop relationships and maintain regular communication with individual investors and select buy-side and sell-side contacts to provide up to date information about events and market trends affecting Parabilis, with the goal of communicating our long-term vision. - Ensure the development of supporting documents, such as analyst consensus models, investor analytics and interpretation, company valuation spreadsheets, investor presentations for conferences and road shows, quarterly earnings scripts, Q&A for SMT, and all press releases related to the financial community. - Support Finance and Legal in developing finance-related investor communications and filings (e.g., quarterly earnings calls, 10-K, etc.). - Serve as primary person to handle incoming inquiries from the media and investors. Record and summarize all investor and analyst contact. - Proactively engage investors and sell-side analysts to articulate the strategy of and status of Parabilis’ progress. - Work productively and frequently with the Executive Team to understand the timing and impact of business events. - Develop a thorough understanding of Parabilis’ pipeline and corporate strategy to support the delivery of our strategy, milestones, and inflection points clearly, compellingly, and compliantly to internal and external audiences. - Create targeting strategy for prospective investors; establish close relationships with key investors and analysts. - Keep abreast of industry trends and competitive landscape to both proactively and reactively adjust plans, messaging and manage relationships that may be impacted. - Monitor Wall Street analysts’ models and estimates, compile and communicate quarterly consensus for internal and external stakeholders. - Set the plan to execute investor conference and events. - Collaborate with Corporate Communications to originate and maintain investor-facing materials, including financial results press releases, investor presentations, conference call scripts, Q&As, IR website and backgrounders. Qualifications - Bachelor of Arts or Bachelor of Science degree required, advanced degree a plus. - Minimum of 12+ years’ experience with a focus on investor relations, finance, equity research or investment banking; public company experience required. Biotech experience preferred. - Strong knowledge of the strategy and individual investors appropriate now and for the next several years for Parabilis and our evolving story. - Ideally strong familiarity with both US and ex-US investors. - A proactive, strategic approach to investor relations and communications. - Ability to relay deep science to external stakeholders and must possess a strong understanding of general science and drug development. - Existing relationships within the financial, industry analyst, media, and institutional investor communities. - Outstanding oral and written communications and presentation skills. - Strong analytical skills, proficient with modern tools such as Claude Code. - Proven ability to plan, organize and execute IR-related events. - Must be able to collaborate effectively with executives and senior leaders; able to work collaboratively across functions. - Demonstrated ability to develop, establish and maintain relationships with healthcare investors and research analysts. - Ability to travel up to 20%. Core Values Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit. - Growth-Minded. We’re inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable. - In(ter)dependent. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options. - Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact. - All-In. We’re All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history. The base salary target for this position is $255,000-$340,000 per year, depending on experience, qualifications, and internal practices. Parabilis’s total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees’ overall well-being. As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. 30 Acorn Park Drive | Cambridge, MA 02140 | www.parabilismed.com

Head of Investor Relations

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