About Karius Karius is a venture-backed life science company transforming how pathogens and other microbes are detected throughout the body. By unlocking the information present in microbial cell-free DNA, we help physicians solve some of their most challenging infectious disease cases, accelerate biomarker discovery and clinical trials for industry partners, and ultimately reduce patient suffering worldwide. Position Summary This is an opportunity to join a growing life sciences company at the forefront of infectious disease diagnostics. Karius is expanding the adoption of its proprietary next-generation sequencing test across hospitals and health systems in the United States. Joining Karius offers the chance to accelerate your career while contributing to a mission that has a direct impact on patient care. The Inside Sales Representative (ISR) plays a critical role in Karius’ commercial strategy by driving proactive outbound engagement and early-stage opportunity creation within a defined, region-based territory. The ISR focuses on initiating new conversations, securing meetings, and creating early commercial momentum, particularly within low-activity or early-stage hospital accounts. Working in close partnership with Clinical Sales Managers (CSMs) and Medical Science Liaisons (MSLs), the ISR owns the front end of the customer journey, progressing opportunities to a qualified meeting and ensuring a smooth handoff to the field team for continued development. Key ISR Job Functions Key ISR job functions include, but are not limited to, the following: Outbound Prospecting & Meeting Generation - Execute proactive outbound calling and multi-channel outreach to initiate conversations with targeted hospital stakeholders - Design and implement structured prospecting strategies and outreach cadences - Secure qualified meetings with appropriate clinical, laboratory, and administrative decision-makers Early-Stage Account Engagement - Own early engagement for assigned low-volume or low-activity hospital and health system accounts - Identify unmet needs, access gaps, and opportunities for further engagement - Progress accounts to a defined next step, culminating in a qualified meeting for CSM/MSL handoff Event and Program Conversion - Support regional events, speaker programs, and conferences through pre-event outreach and post-event follow-up - Convert event engagement into scheduled meetings and qualified opportunities Opportunity & Activity Management - Accurately document outreach, interactions, and meetings in Salesforce - Maintain visibility into ISR-owned activity, opportunity progression, and handoff status Why Should You Join Us? Karius is advancing infectious disease diagnostics through innovations in genomics, machine learning, and clinical science. Our platform delivers unprecedented insight into the microbial landscape, providing physicians with powerful tools to diagnose complex infections and improve patient outcomes. As part of the Karius team, your work will have a meaningful and measurable impact on patient care at scale. Reports to: Regional Sales Director  Location: Greater Dallas - Fort Worth, Texas area   Primary Responsibilities - Proactively introduce Karius’ diagnostic technology to key hospital stakeholders involved in diagnostic decision-making Source new opportunities through structured outbound calling and targeted outreach - Secure and schedule qualified meetings for CSMs and MSLs - Qualify leads by identifying clinical needs, institutional priorities, and appropriate next steps - Conduct introductory, high-level technical conversations to assess fit and interest - Own early-stage opportunity progression through meeting creation and documented handoff - Support early evaluations by facilitating access and coordination prior to field ownership - Partner with CSMs/MSLs to align on targeting, messaging, and territory priorities - Support regional meetings, events, and programs by driving pre- and post-event engagement - Collaborate with Sales, Marketing, and Product teams to share market insights and feedback - Maintain accurate CRM documentation related to ISR-owned outreach, meetings, and opportunities - Participate in training, team meetings, and industry events as required - Contribute to a collaborative, high-performance commercial culture What Success Looks Like in This Role - Consistent, high-quality outbound activity - Meetings secured with appropriate hospital stakeholders - Clear opportunity progression and clean handoffs to the field - Strong partnership and alignment with CSM and MSL counterparts Travel Approximately 15% travel for meetings, training, and co-field engagement. Physical Requirements This role may require extended periods of sitting or standing. Work is generally performed remotely or in the field. Position Requirements - Bachelor’s degree; advanced degree or MBA a plus - 2+ years of sales or business development experience in life sciences, diagnostics, medical devices, or pharmaceuticals - Demonstrated success introducing novel or transformational products in complex clinical environments - Strong communication, organization, and prioritization skills - Ability to engage a wide range of hospital stakeholders with confidence and professionalism - Experience working collaboratively within a team-based commercial model - Proficiency with CRM systems (Salesforce preferred) Personal Qualifications - Entrepreneurial mindset and comfort operating in a fast-paced, evolving environment - Strong sense of ownership and accountability - Collaborative, team-oriented approach - High integrity, professionalism, and ethical standards - Passion for improving patient care and advancing Karius’ mission Disclaimer The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.   At Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.com and we will accommodate qualified individuals with disabilities.  About Karius Karius is a venture-backed life science company transforming how pathogens and other microbes are detected throughout the body. By unlocking the information present in microbial cell-free DNA, we help physicians solve some of their most challenging infectious disease cases, accelerate biomarker discovery and clinical trials for industry partners, and ultimately reduce patient suffering worldwide. Position Summary This is an opportunity to join a growing life sciences company at the forefront of infectious disease diagnostics. Karius is expanding the adoption of its proprietary next-generation sequencing test across hospitals and health systems in the United States. Joining Karius offers the chance to accelerate your career while contributing to a mission that has a direct impact on patient care. The Inside Sales Representative (ISR) plays a critical role in Karius’ commercial strategy by driving proactive outbound engagement and early-stage opportunity creation within a defined, region-based territory. The ISR focuses on initiating new conversations, securing meetings, and creating early commercial momentum, particularly within low-activity or early-stage hospital accounts. Working in close partnership with Clinical Sales Managers (CSMs) and Medical Science Liaisons (MSLs), the ISR owns the front end of the customer journey, progressing opportunities to a qualified meeting and ensuring a smooth handoff to the field team for continued development. Key ISR Job Functions Key ISR job functions include, but are not limited to, the following: Outbound Prospecting & Meeting Generation - Execute proactive outbound calling and multi-channel outreach to initiate conversations with targeted hospital stakeholders - Design and implement structured prospecting strategies and outreach cadences - Secure qualified meetings with appropriate clinical, laboratory, and administrative decision-makers Early-Stage Account Engagement - Own early engagement for assigned low-volume or low-activity hospital and health system accounts - Identify unmet needs, access gaps, and opportunities for further engagement - Progress accounts to a defined next step, culminating in a qualified meeting for CSM/MSL handoff Event and Program Conversion - Support regional events, speaker programs, and conferences through pre-event outreach and post-event follow-up - Convert event engagement into scheduled meetings and qualified opportunities Opportunity & Activity Management - Accurately document outreach, interactions, and meetings in Salesforce - Maintain visibility into ISR-owned activity, opportunity progression, and handoff status Why Should You Join Us? Karius is advancing infectious disease diagnostics through innovations in genomics, machine learning, and clinical science. Our platform delivers unprecedented insight into the microbial landscape, providing physicians with powerful tools to diagnose complex infections and improve patient outcomes. As part of the Karius team, your work will have a meaningful and measurable impact on patient care at scale. Reports to: Regional Sales Director  Location: Greater Dallas - Fort Worth, Texas area   Primary Responsibilities - Proactively introduce Karius’ diagnostic technology to key hospital stakeholders involved in diagnostic decision-making Source new opportunities through structured outbound calling and targeted outreach - Secure and schedule qualified meetings for CSMs and MSLs - Qualify leads by identifying clinical needs, institutional priorities, and appropriate next steps - Conduct introductory, high-level technical conversations to assess fit and interest - Own early-stage opportunity progression through meeting creation and documented handoff - Support early evaluations by facilitating access and coordination prior to field ownership - Partner with CSMs/MSLs to align on targeting, messaging, and territory priorities - Support regional meetings, events, and programs by driving pre- and post-event engagement - Collaborate with Sales, Marketing, and Product teams to share market insights and feedback - Maintain accurate CRM documentation related to ISR-owned outreach, meetings, and opportunities - Participate in training, team meetings, and industry events as required - Contribute to a collaborative, high-performance commercial culture What Success Looks Like in This Role - Consistent, high-quality outbound activity - Meetings secured with appropriate hospital stakeholders - Clear opportunity progression and clean handoffs to the field - Strong partnership and alignment with CSM and MSL counterparts Travel Approximately 15% travel for meetings, training, and co-field engagement. Physical Requirements This role may require extended periods of sitting or standing. Work is generally performed remotely or in the field. Position Requirements - Bachelor’s degree; advanced degree or MBA a plus - 2+ years of sales or business development experience in life sciences, diagnostics, medical devices, or pharmaceuticals - Demonstrated success introducing novel or transformational products in complex clinical environments - Strong communication, organization, and prioritization skills - Ability to engage a wide range of hospital stakeholders with confidence and professionalism - Experience working collaboratively within a team-based commercial model - Proficiency with CRM systems (Salesforce preferred) Personal Qualifications - Entrepreneurial mindset and comfort operating in a fast-paced, evolving environment - Strong sense of ownership and accountability - Collaborative, team-oriented approach - High integrity, professionalism, and ethical standards - Passion for improving patient care and advancing Karius’ mission Disclaimer The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.   At Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.com and we will accommodate qualified individuals with disabilities. 

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