About Iovance Biotherapeutics, Inc.  Iovance Biotherapeutics, Inc.  is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com. Amtagvi® and its accompanying design marks, Proleukin®, Iovance®, and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners. Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com. Overview The Associate Director, Medical Affairs (Medical Science Liaison) is a field-based individual contributor who advances the medical strategy for Iovance’s developmental and marketed products through high-impact scientific exchange, generation and communication of actionable medical insights, and cross-functional partnership. This role builds and sustains relationships with regional and national external experts (e.g., key opinion leaders, investigators, and healthcare systems) and supports clinical trial site identification and execution, consistent with applicable laws, regulations, and company policies. The Associate Director operates with a high degree of independence, provides scientific and strategic input to internal teams, and contributes to consistent field medical standards and processes through collaboration and sharing of best practices (without direct people-management responsibility). Region: Southeast (Florida (preferred), Georgia, South Carolina, or Alabama) Essential Functions and Responsibilities - Advance the medical strategy within the assigned territory by delivering fair-balanced, evidence-based scientific exchange and by representing Iovance as a credible partner to the healthcare community - Deliver high-quality scientific and clinical presentations on disease state(s) and Iovance products (approved and pipeline) to internal and external audiences; tailor content to audience needs and ensure alignment with approved materials and compliance requirements - Identify, map, and profile external experts (e.g., KOLs, investigators, advocacy and healthcare system stakeholders) and develop territory engagement plans to inform medical priorities and scientific collaboration opportunities - Develop and sustain relationships with healthcare professionals and clinical investigators in academic and community settings to support scientific activities aligned with the medical plan (e.g., publications, advisory boards, investigator-initiated research support, and clinical trials, as applicable) - Collect, synthesize, and communicate high-quality field medical insights using approved tools and processes; identify trends, elevate insights to internal stakeholders, and contribute to insight-to-action discussions - Provide scientific support for Medical Affairs activities and scientific sessions at key congresses/meetings; plan and execute congress engagement in coordination with internal stakeholders - Build strong cross-functional partnerships (e.g., Medical Affairs, Clinical Science, Clinical Operations, Market Access, and Commercial) to ensure coordinated execution of the medical plan and appropriate, compliant information flow - Model inclusive, professional behaviors and contribute to a collaborative team culture through respectful communication and reliable follow-through with internal and external partners - Apply strong problem-solving and prioritization skills to address complex field challenges; anticipate needs of patients and the healthcare community and recommend solutions consistent with medical strategy - Demonstrate an established scientific/clinical foundation and the ability to communicate complex data clearly, accurately, and compliantly to a range of audiences - Provide informal peer support (e.g., onboarding support, sharing best practices, and serving as a subject-matter resource) and contribute to field medical capability-building initiatives, as needed, without direct people-management responsibility - Operate in accordance with applicable laws, regulations, and company policies (e.g., scientific exchange, privacy, adverse event reporting) and promptly escalate questions or issues through established channels - Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics. - Perform miscellaneous duties as assigned. Travel - Ability and willingness to travel up to 60% of the time within the assigned territory, as business needs require Required Education, Skills, and Knowledge - Advanced scientific degree (MD, PhD, PharmD) with a minimum of 8 years of relevant pharmaceutical, biotechnology, clinical, or healthcare experience; or licensed healthcare professional (RN, NP, CNS, PA, or equivalent) with a Master's degree or higher and a minimum of 10 years of relevant experience. - Minimum of 5 years of experience as a Medical Science Liaison or in a comparable field-based medical, clinical, scientific, or oncology-related role. - Demonstrated experience establishing and maintaining productive relationships with healthcare professionals, investigators, and other external experts. - Strong understanding of clinical data and the ability to communicate scientific information clearly and accurately to a variety of audiences. - Proven skills in planning, prioritization, decision-making, problem-solving, and execution. - Experience leading complex projects and coordinating work across multiple functions. - Excellent written, verbal, and presentation skills. - Ability to operate independently while working effectively within a matrix organization. - Strong meeting management, organizational, and follow-through skills. - Ability to manage multiple priorities and meet deadlines in a fast-paced environment. - Sound judgment and ability to adapt to changing business and customer needs. Preferred Education, Skills, and Knowledge - Medical affairs, MSL, clinical, or scientific experience in oncology and/or hematology. - Experience in cellular therapy, immuno-oncology, melanoma, non-small cell lung cancer (NSCLC), or other relevant oncology therapeutic areas. - Established knowledge of the assigned geography, treatment centers, and key external experts. - Understanding of oncology clinical trials, evidence generation, and the oncology treatment landscape. - Knowledge of regulatory, compliance, and ethical requirements applicable to field-based medical roles. - Experience leading regional or national medical affairs projects and initiatives. - Experience supporting investigator-sponsored studies, clinical trial activities, advisory boards, congress planning, or medical education programs. - Ability to gather, analyze, and communicate field insights to help inform medical affairs activities and business planning. - Experience managing project budgets and resources. Demonstrated success working across Medical Affairs, Clinical Development, Commercial, Market Access, and other cross-functional teams to support organizational objectives. The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodation may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request accommodation. Physical Demands and Activities Required - Ability to travel, usually within the US; field-based position with potential for significant travel - Ability to remain in a stationary position (sitting or standing) for extended periods, as needed, with or without reasonable accommodation - Ability to move within a home or office environment and to position and transport typical work materials and equipment, with or without reasonable accommodation - Ability to review and analyze scientific/medical information and work on a computer for extended periods, with or without reasonable accommodation - Ability to perform repetitive hand/wrist motions associated with computer and mobile device use, with or without reasonable accommodation - Ability to communicate and exchange information with internal and external stakeholders, with or without reasonable accommodation Cognitive and organizational requirements: Ability to apply sound judgment; analyze and interpret information; solve problems; maintain confidentiality and discretion; manage multiple priorities; and meet timelines, with or without reasonable accommodation Work Environment This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. #li-remote The annual base salary we reasonably expect to pay is listed. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of the role, job duties/requirements, and relevant education, experience and skills. Pay Transparency $185,000—$210,000 USD The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Associate Director, Medical Affairs (Medical Science Liaison) – Southeast Region

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